Which layer of skin contains blood vessels and nerves?

The dermis is the layer of skin that contains blood vessels and nerves, making it essential for delivering nutrients to the skin and providing sensory information. This layer is situated beneath the epidermis, which is the outermost layer of the skin and primarily composed of keratinized cells that offer a protective barrier. The dermis itself is rich in connective tissue, collagen, and elastin, contributing to the skin's strength and elasticity.

Within the dermis, blood vessels play a critical role in thermoregulation and the overall health of the skin by supplying oxygen and nutrients. Nerves found in this layer enable the sensation of touch, pain, and temperature. This functionality is crucial, as it allows the skin to respond to external stimuli and maintain the body's homeostasis.

The hypodermis, while it does contain larger blood vessels and nerves, functions more as an insulating layer and a pad for the skin, primarily composed of fat and connective tissue. The epidermis, being the outer layer, does not contain blood vessels or nerves; it relies on the dermis for these resources. Lastly, the stratum corneum is a sub-layer of the epidermis, consisting of dead keratinized cells, also lacking blood supply and nerve endings.