Which term describes skin that has lost its pigmentation?

The term that describes skin that has lost its pigmentation is leukoderma. This condition results in areas of skin that are lighter than the surrounding skin due to a decrease in melanin production or other underlying causes. Leukoderma is often characterized by patches of depigmented skin, which can occur due to various factors, including autoimmune responses, genetics, or skin diseases.

While vitiligo can also lead to loss of pigmentation and appears as white patches on the skin, it is a specific autoimmune condition leading to depigmentation as well. Albinism refers to a genetic condition that results in a lack of melanin pigmentation throughout the body, affecting hair, skin, and eyes. Hyperpigmentation, on the other hand, is the opposite of depigmentation, involving excess melanin production, resulting in darker patches of skin. Thus, leukoderma is the most fitting term for skin that has lost its pigmentation.